2025
Doering, Elena; Hoenig, Merle C.; Giehl, Kathrin; Dzialas, Verena; Andrassy, Grégory; Bader, Abdelmajid; Bauer, Andreas; Elmenhorst, David; Ermert, Johannes; Frensch, Silke; Jäger, Elena; Jessen, Frank; Krapf, Philipp; Kroll, Tina; Lerche, Christoph; Lothmann, Julia; Matusch, Andreas; Neumaier, Bernd; Onur, Oezguer A.; Ramirez, Alfredo; Richter, Nils; Sand, Frederik; Tellmann, Lutz; Theis, Hendrik; Zeyen, Philip; van Eimeren, Thilo; Drzezga, Alexander; Bischof, Gérard N.
“Fill States”: PET-derived Markers of the Spatial Extent of Alzheimer Disease Pathology Journal Article
In: Radiology, vol. 314, no. 3, 2025, ISSN: 1527-1315.
Abstract | Links | BibTeX | Tags: Alzheimer, Amyloid PET, Biomarker, FDG PET, Spatial extent, Tau PET
@article{Doering2025,
title = {“Fill States”: PET-derived Markers of the Spatial Extent of Alzheimer Disease Pathology},
author = {Elena Doering and Merle C. Hoenig and Kathrin Giehl and Verena Dzialas and Grégory Andrassy and Abdelmajid Bader and Andreas Bauer and David Elmenhorst and Johannes Ermert and Silke Frensch and Elena Jäger and Frank Jessen and Philipp Krapf and Tina Kroll and Christoph Lerche and Julia Lothmann and Andreas Matusch and Bernd Neumaier and Oezguer A. Onur and Alfredo Ramirez and Nils Richter and Frederik Sand and Lutz Tellmann and Hendrik Theis and Philip Zeyen and Thilo van Eimeren and Alexander Drzezga and Gérard N. Bischof},
doi = {10.1148/radiol.241482},
issn = {1527-1315},
year = {2025},
date = {2025-03-01},
urldate = {2025-03-01},
journal = {Radiology},
volume = {314},
number = {3},
publisher = {Radiological Society of North America (RSNA)},
abstract = {<jats:p> The spatial extent of amyloid, tau, and neurodegeneration, derived from PET imaging, has higher diagnostic performance for cognitive impairment severity compared with standardized uptake value ratios. </jats:p>},
keywords = {Alzheimer, Amyloid PET, Biomarker, FDG PET, Spatial extent, Tau PET},
pubstate = {published},
tppubtype = {article}
}
2021
Pfeil, Julia; Hoenig, Merle C.; Doering, Elena; van Eimeren, Thilo; Drzezga, Alexander; Bischof, Gérard N.
Unique regional patterns of amyloid burden predict progression to prodromal and clinical stages of Alzheimer's disease Journal Article
In: Neurobiology of Aging, vol. 106, pp. 119–129, 2021, ISSN: 0197-4580.
Links | BibTeX | Tags: Alzheimer, Amyloid PET
@article{Pfeil2021,
title = {Unique regional patterns of amyloid burden predict progression to prodromal and clinical stages of Alzheimer's disease},
author = {Julia Pfeil and Merle C. Hoenig and Elena Doering and Thilo van Eimeren and Alexander Drzezga and Gérard N. Bischof},
doi = {10.1016/j.neurobiolaging.2021.06.014},
issn = {0197-4580},
year = {2021},
date = {2021-10-00},
urldate = {2021-10-00},
journal = {Neurobiology of Aging},
volume = {106},
pages = {119--129},
publisher = {Elsevier BV},
keywords = {Alzheimer, Amyloid PET},
pubstate = {published},
tppubtype = {article}
}
Seemiller, Joseph; Bischof, Gérard N.; Hoenig, Merle C.; Tahmasian, Masoud; van Eimeren, Thilo; Drzezga, Alexander
Indication of retrograde tau spreading along Braak stages and functional connectivity pathways Journal Article
In: Eur J Nucl Med Mol Imaging, vol. 48, no. 7, pp. 2272–2282, 2021, ISSN: 1619-7089.
Links | BibTeX | Tags: Alzheimer, Functional connectivity, Tau PET
@article{Seemiller2021,
title = {Indication of retrograde tau spreading along Braak stages and functional connectivity pathways},
author = {Joseph Seemiller and Gérard N. Bischof and Merle C. Hoenig and Masoud Tahmasian and Thilo van Eimeren and Alexander Drzezga},
doi = {10.1007/s00259-020-05183-1},
issn = {1619-7089},
year = {2021},
date = {2021-07-00},
urldate = {2021-07-00},
journal = {Eur J Nucl Med Mol Imaging},
volume = {48},
number = {7},
pages = {2272--2282},
publisher = {Springer Science and Business Media LLC},
keywords = {Alzheimer, Functional connectivity, Tau PET},
pubstate = {published},
tppubtype = {article}
}
2020
Hoenig, Merle C.; Willscheid, Niclas; Bischof, Gérard N.; van Eimeren, Thilo; Drzezga, Alexander
Assessment of Tau Tangles and Amyloid-β Plaques Among Super Agers Using PET Imaging Journal Article
In: JAMA Netw Open, vol. 3, no. 12, 2020, ISSN: 2574-3805.
Links | BibTeX | Tags: Alzheimer, Amyloid PET, Brain age, Super aging, Tau PET
@article{Hoenig2020,
title = {Assessment of Tau Tangles and Amyloid-β Plaques Among Super Agers Using PET Imaging},
author = {Merle C. Hoenig and Niclas Willscheid and Gérard N. Bischof and Thilo van Eimeren and Alexander Drzezga},
doi = {10.1001/jamanetworkopen.2020.28337},
issn = {2574-3805},
year = {2020},
date = {2020-12-01},
urldate = {2020-12-01},
journal = {JAMA Netw Open},
volume = {3},
number = {12},
publisher = {American Medical Association (AMA)},
keywords = {Alzheimer, Amyloid PET, Brain age, Super aging, Tau PET},
pubstate = {published},
tppubtype = {article}
}
2019
Hoenig, Merle C.; Bischof, Gérard N.; Onur, Özgür A.; Kukolja, Juraj; Jessen, Frank; Fliessbach, Klaus; Neumaier, Bernd; Fink, Gereon R.; Kalbe, Elke; Drzezga, Alexander; van Eimeren, Thilo
Level of education mitigates the impact of tau pathology on neuronal function Journal Article
In: Eur J Nucl Med Mol Imaging, vol. 46, no. 9, pp. 1787–1795, 2019, ISSN: 1619-7089.
Links | BibTeX | Tags: Alzheimer, Cognitive reserve, Education, Tau PET
@article{2019b,
title = {Level of education mitigates the impact of tau pathology on neuronal function},
author = {Merle C. Hoenig and Gérard N. Bischof and Özgür A. Onur and Juraj Kukolja and Frank Jessen and Klaus Fliessbach and Bernd Neumaier and Gereon R. Fink and Elke Kalbe and Alexander Drzezga and Thilo van Eimeren},
doi = {10.1007/s00259-019-04342-3},
issn = {1619-7089},
year = {2019},
date = {2019-08-00},
urldate = {2019-08-00},
journal = {Eur J Nucl Med Mol Imaging},
volume = {46},
number = {9},
pages = {1787--1795},
publisher = {Springer Science and Business Media LLC},
keywords = {Alzheimer, Cognitive reserve, Education, Tau PET},
pubstate = {published},
tppubtype = {article}
}
2018
Hoenig, Merle C; Bischof, Gérard N; Seemiller, Joseph; Hammes, Jochen; Kukolja, Juraj; Onur, Özgür A; Jessen, Frank; Fliessbach, Klaus; Neumaier, Bernd; Fink, Gereon R; van Eimeren, Thilo; Drzezga, Alexander
Networks of tau distribution in Alzheimer’s disease Journal Article
In: vol. 141, no. 2, pp. 568–581, 2018, ISSN: 1460-2156.
Links | BibTeX | Tags: Alzheimer, Functional connectivity, Tau PET
@article{Hoenig2018,
title = {Networks of tau distribution in Alzheimer’s disease},
author = {Merle C Hoenig and Gérard N Bischof and Joseph Seemiller and Jochen Hammes and Juraj Kukolja and Özgür A Onur and Frank Jessen and Klaus Fliessbach and Bernd Neumaier and Gereon R Fink and Thilo van Eimeren and Alexander Drzezga},
doi = {10.1093/brain/awx353},
issn = {1460-2156},
year = {2018},
date = {2018-02-01},
urldate = {2018-02-01},
volume = {141},
number = {2},
pages = {568--581},
publisher = {Oxford University Press (OUP)},
keywords = {Alzheimer, Functional connectivity, Tau PET},
pubstate = {published},
tppubtype = {article}
}
2017
Hoenig, Merle C.; Bischof, Gérard Nisal; Hammes, Jochen; Faber, Jennifer; Fliessbach, Klaus; van Eimeren, Thilo; Drzezga, Alexander
Tau pathology and cognitive reserve in Alzheimer's disease Journal Article
In: Neurobiology of Aging, vol. 57, pp. 1–7, 2017, ISSN: 0197-4580.
Links | BibTeX | Tags: Alzheimer, Cognitive reserve, Education, Tau PET
@article{Hoenig2017,
title = {Tau pathology and cognitive reserve in Alzheimer's disease},
author = {Merle C. Hoenig and Gérard Nisal Bischof and Jochen Hammes and Jennifer Faber and Klaus Fliessbach and Thilo van Eimeren and Alexander Drzezga},
doi = {10.1016/j.neurobiolaging.2017.05.004},
issn = {0197-4580},
year = {2017},
date = {2017-09-00},
urldate = {2017-09-00},
journal = {Neurobiology of Aging},
volume = {57},
pages = {1--7},
publisher = {Elsevier BV},
keywords = {Alzheimer, Cognitive reserve, Education, Tau PET},
pubstate = {published},
tppubtype = {article}
}