Elena Doering, MSc

Elena Doering completed her master’s thesis on the effects of vibrotactile cueing on freezing of gait in Parkinson’s disease in 2019. She has recently joined the MMNI group as a PhD candidate, where she will investigate molecular and neuronal mechanisms underlying neurodegeneration in Alzheimer’s disease, such as for example tau and amyloid accumulation in the brain. Her research interest further extends into the domain of machine learning and artificial intelligence methodologies.

See me on linkedin.
See me on Researchgate.

Publications: 

Doering, E., Pukropski, A., Krumnack, U., Schaffland, A. Automatic Detection and Counting of Malaria Parasite-Infected Blood Cells. Proceedings of MICAD2020 (in print). Lecture Notes in Electrical Engineering.

 

Michelle Meier, cand. med.

My research focuses on improving imaging-derived diagnosis of Parkinsonian Syndromes via artificial intelligence. Therefore, I explore tools of automatizing the image analysis process by implementing various methods in the field of machine learning and deep learning.

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Contact:

Michelle Meier
MD student

 

Hendrik Theis, M.D.

Hendrik Theis is a resident physician at the Department of Neurology at the University Hospital of Cologne and a researcher in the Multimodal Imaging Group. His research focus is the dopaminergic modulation of brain networks. He is investigating changes of fronto-striatal connectivity in Parkinson’s patients with impulse-control disorders and he is also interested in reward learning in obesity.

 

Publications: 

Hammes, J, Theis, H, Giehl, K, Hoenig, MC, Greuel, A, Tittgemeyer, M et al.. Dopamine metabolism of the nucleus accumbens and fronto-striatal connectivity modulate impulse control. Brain. 2019;142 (3):733-743.

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Contact:

Hendrik Theis
M.D.

 

Merle Hönig, M.Sc.

Merle Hönig’s research interest is focused on the investigation of gene-environment interactions in Alzheimer’s disease (AD) using a multimodal imaging approach. As part of her PhD project, she elucidates the role of lifetime factors such as education, occupation, nutrition and physical activity in regard to the occurrence and extent of AD-related brain pathology and changes in network function. In addition, she is interested in epigenetic changes underlying AD and how these changes are associated with lifetime factors and neuropathology. The overall aim of her project is to contribute to the understanding of the underlying mechanisms of sporadic AD.

Selected publications:

Hönig MC, Bischof GN, Hammes J, Faber J, Fliessbach K, van Eimeren T, et al. Tau pathology and cognitive reserve in Alzheimer’s disease. Neurobiol Aging. 2017 Sep;57:1–7.

Hönig MC, Bischof GN, Seemiller J, Hammes J, Kukolja J, Onur Ö, Jessen F, Fliessbach K, Neumaier B, Fink GR, van Eimeren T, Drzezga A. Networks of tau distribution in Alzheimer’s disease. Brain, 2018

Curriculum Vitae (Hoenig_CV)

Kathrin Giehl, M.Sc.

Kathrin Giehl’s primary research focus is to advance the understanding of underlying neural mechanisms involved in Parkinson’s and Huntington’s disease. Concerning Parkinson’s disease, she is particularly interested in elucidating mechanism responsible for distinct cognitive impairments, which are frequently observed in this patient cohort, and to investigate the effects of cognitive training on a neural level in order to ameliorate these difficulties. Moreover, she is interested in better understanding the role of tau in the clinical presentation and progression of Huntington’s disease. For her research, she utilizes behavioral paradigms and various neuroimaging methods, such as functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET).

Selected publications:

Tahmasian M, Eickhoff SB, Giehl K, Schwartz F, Herz DM, Drzezga A, et al. Resting-state functional reorganization in Parkinson’s disease: An activation likelihood estimation meta-analysis. Cortex. 2017 Jul; 92:119–38

Zokaei N, Giehl K, Sillence A, Neville MJ, Karpe F, Nobre AC, Husain M. Sex and APOE: A memory advantage in male APOE ε4 carriers in midlife. Cortex. 2017 Mar 31; 88:98-105

Chong TT, Apps M, Giehl K, Sillence A, Grima LL, Husain M. Neurocomputational mechanisms    underlying subjective valuation of effort costs. PLoS biology. 2017 Feb 24;15(2): e1002598

Hammes J, Bischof GN, Giehl K, Faber J, Drzezga A, Klockgether T, et al. Elevated in vivo [18F]-AV-1451 uptake in a patient with progressive supranuclear palsy. Mov. Disord. 2017 Jan;32(1):170–1

Rolinski M, Zokaei N, Baig F, Giehl K, Quinnell T, Zaiwalla Z, Mackay CE, Husain M, Hu MTM. Visual short-term memory deficits in REM sleep behaviour disorder mirror those in Parkinson’s disease. Brain. 2015 Nov 18; 139(1): 47-53.

Curriculum Vitae  (download CV as pdf)

Contact:

Kathrin Giehl, M.Sc.
PhD student

Jochen Hammes, MD

Dr. Jochen Hammes is a resident physician at the Department of Nuclear Medicine at the University Hospital of Cologne and a postdoctoral researcher in the Multimodal Imaging Group. He is especially interested in developing algorithmic methods in multimodal imaging research. See Jochen Hammes‘ profile on Researchgate.

 

 

Selected publications:
Hammes J, Täger P, Drzezga A; EBONI: A tool for automated quantification of bone metastasis load in PSMA PET/CT, J. Nucl. Med. 2017 (accepted for publication)

Hammes J, Leuwer I, Bischof GN, Drzezga A, van Eimeren T; Multimodal correlation of dynamic [18F]-AV-1451 perfusion PET and neuronal hypometabolism in [18F]-FDG PET; Eur J Nucl Med Mol Imaging 2017.

Hammes J, Bischof GN, Drzezga A: Molecular imaging in early diagnosis, differential diagnosis and follow-up of patients with neurodegenerative diseases; Clin Transl Imaging, 2017; 5: 465.

 

Curriculum vitae (Download CV as PDF):
2015-present
Resident physician and postdoctoral researcher at Department of Nuclear Medicine, University Hospital Cologne
Algorithmic methods in imaging research
Imaging in neurodegenerative diseases

2014-2015
Manager for product development and IT at BetterDoc GmbH, Cologne
Product development, Database design, Userinterface design,
head of development team

2013-2014
Resident physician in neurology
Clinic for Neurology and Palliative Medicine, Clinics of the City of Cologne

2009-2013
Doctoral studies at Dept. of Nuclear Medicine, University Hospital Cologne
Thesis: GATE based Monte Carlo simulation of planar scintigraphy to estimate the nodular dose in radioiodine therapy for autonomous thyroid adenoma

2007-2013
Medical school
University Hospital Cologne, St. Claraspital Basel (CH), Kantonsspital St. Gallen (CH)

 

Contact
Jochen Hammes, MD
Contact: webmaster@mmni.de